- Single-molecule and Membrane Biophysics.
- Biosensors and Functional Biomaterials.
- Membrane protein design.
The right-hand panel illustrates a 3 nm pore in silicon nitride. Image was taken in STEM mode on the FEI Tecnai F20 TEM/STEM at the Cornell Center for Materials Research (CCMR). The left-hand panel shows a single-channel electrical recording of transient current blockades produced by individual double-stranded DNA molecules.
(Feb. 17, 2020)
Professor Liviu Movileanu and Avinash Thakur Ph.D. presented their research on molecular "fishing."
(Jan. 22, 2019)
Ph.D. candidate Avinash “Avi” Thakur helps design nanomaterials that could improve cancer detection
(Dec. 10, 2018)
Professor Liviu Movileanu designs biosensors that target proteins interacting with one another
(Sept. 6, 2018)
Professor Liviu Movileanu develops biosensors to identify proteins in leukemia, cancer
(Nov. 21, 2017)
Aaron Wolfe is the chief operating officer of his biotech company, Ichor Therapeutics.
1997 Ph.D. in Biophysics
University of Bucharest 1990 M.S. Polymer Physics
University of Bucharest 1989 B.S. in Physics
University of Bucharest
A.J. Wolfe, J.F. Gugel, M. Chen, and L. Movileanu, 2018, Detergent Desorption of Membrane Proteins Exhibits Two Kinetic Phases, J. Phys. Chem. Lett. 9, 1913-1919. PMCID: PMC5908730
A.J. Wolfe, W. Si, F. Zhang, AR. Blanden, Y.C. Hsueh, J.F. Gugel, B. Pham, M. Chen, S.N. Loh, S. Rozovsky, A. Aksimentiev, and L. Movileanu, 2017, Quantification of Membrane Protein-Detergent Complex Interactions, J. Phys. Chem. B 121(44), 10228-10241. PMCID: PMC5680101
A.K. Thakur, M.G. Larimi, K. Gooden, and L. Movileanu, 2017, Aberrantly large single-channel conductance of polyhistidine arm-containing protein nanopores, Biochemistry 56(36), 4895-4905. PMCID: PMC5595664
A.J. Wolfe, Y.C. Hsueh, A.R. Blanden, M.M. Mohammad, B. Pham, A.K. Thakur, S.N. Loh, M. Chen, and L. Movileanu, 2017, Interrogating Detergent Desolvation of Nanopore-forming Proteins by Fluorescence Polarization Spectroscopy, Anal. Chem. 89(15), 8013-8020. PMCID: PMC5558884
S. Couoh-Cardel, Y.C. Hsueh, S. Wilkens, and L. Movileanu, 2016, Yeast V-ATPase Proteolipid Ring Acts as a Large-conductance Transmembrane Protein Pore, Sci. Rep. 6, 24774. PMCID: PMC4838861