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Syracuse University, College of Arts and Sciences

Melanie Blanden

Melanie Blanden portrait

Assistant Teaching Professor




366 Life Sciences Complex

Teaching Experience and Interests

I have been teaching undergraduate biochemistry and related courses since 2017 when I began teaching at Utica College. My experience includes teaching chemistry, biology, nursing, physical therapy, and health studies majors. I am interested in bridging the content of both biology and chemistry in my courses in a way that is accessible to a diverse group of students and encourages active learning and critical thinking.


  • BCM 475: Biochemistry I
  • BCM 476: Biochemistry II
  • BIO 475: Biochemistry Laboratory


  • Ph.D. at Syracuse University in Chemistry (2018)
  • M.Phil at Syracuse University in Chemistry (2013)
  • B.S. at Bay Path University in Forensic Science (2011)

Research Interests

The relationships between enzyme structure and substrate recognition

Selected Publications

Blanden, Melanie. J., Ashok, Sudhat and Hougland, James. L. Mechanisms of CaaX Protein Processing:

Protein Prenylation by FTase and GGTase-I Comprehensive Natural Products III: Chemistry and Biology.


Blanden, Melanie J., Suazo, Kiall F., Hildebrandt, Emily R., Hardgrove, Daniel S., Patel, M., Saunders,

William P., Distefano, Mark D., Schmidt, Walter K., and Hougland, James L. Efficient farnesylation of

“forbidden” C-terminal C(x)3X sequences expands the scope of the prenylated proteome J. Biol. Chem.,

2018, 293 (8), 2770-2785

Shala-Lawrence, Agnesa*, Blanden, Melanie J.*, Krylova, Svetlana M., Gangopadhyay, Soumyashree A.,

Beloborodov, Stanislav S., Hougland, James L., and Krylov, Sergey N. Simultaneous Analysis of a Non-

Lipidated Protein and Its Lipidated Counterpart: Enabling Quantitative Investigation of Protein

Lipidation’s Impact on Cellular Regulation Anal Chem., 2017, 89 (24), 13502-13507 *Co-first Authors

Zhang, Yi, Blanden, Melanie J., Sudheer, Ch., Gangopadhyay, Soumyashree A., Rashidian, Mohammad,

Hougland, James L., and Distefano, Mark D. Simultaneous Site-Specific Dual Protein Labeling Using

Protein Prenyltransferases Bioconjugate Chem., 2015, 26 (12), 2542–2553