Website

www.ichortherapeutics.com

Research Interests

• Translational research
• Biology of aging

Education

• PhD in Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, 2019
• MBA in Risk Management, Concordia University Wisconsin, 2013
• BS in Cellular Biochemistry and Psychology, SUNY Plattsburgh, 2010

Awards & Professional Honors

• 2019 Groundbreaker Achievement Award Nominee, MedTech
• 2018 40 under Forty, CNY Business Journal

Selected Publications

• Grohn, K. J.; Moyer, B. S.; Wortel, D. C.; Fisher, C. M.; Lumen, E.; Bianchi, A. H.; Kelly, K.; Campbell, P. S.; Hagrman, D. E.; Bagg, R. G.; Clement, J.; Wolfe, A. J.; Basso, A.; Nicoletti, C.; Lai, G.; Provinciali, M.; Malavolta, M.; Moody, K. J. C60 in Olive Oil Causes Light-Dependent Toxicity and Does Not Extend Lifespan in Mice. Geroscience 2020. https://doi.org/10.1007/s11357-020-00292-z.
• Milliken, B. T.; Melegari, L.; Smith, G. L.; Grohn, K.; Wolfe, A. J.; Moody, K.; Bou-Abdallah, F.; Doyle, R. P. Fenretinide Binding to the Lysosomal Protein Saposin D Alters Ceramide Solubilization and Hydrolysis. RSC Med. Chem. 2020. https://doi.org/10.1039/D0MD00182A.
• Tian, X.; Firsanov, D.; Zhang, Z.; Cheng, Y.; Luo, L.; Tombline, G.; Tan, R.; Simon, M.; Henderson, S.; Steffan, J.; Goldfarb, A.; Tam, J.; Zheng, K.; Cornwell, A.; Johnson, A.; Yang, J.-N.; Mao, Z.; Manta, B.; Dang, W.; Zhang, Z.; Vijg, J.; Wolfe, A.; Moody, K.; Kennedy, B. K.; Bohmann, D.; Gladyshev, V. N.; Seluanov, A.; Gorbunova, V. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell 2019, 177 (3), 622-638.e22. https://doi.org/10.1016/j.cell.2019.03.043.
• Moody, K. J.; Tinklepaugh, J.; Obert, E.; Grohn, K.; DeRosa, J. R.; Lumen, E.; Moyer, B. S.; Campbell, S.; Wolfe, A. J.; Sleeper, M. B.; Bianchi, A. H.; Fisher, C.; Applegate, J.; Leary, E.; LeClair, N.; Wortel, D.; Doyle, R. P.; Rohrer, B.; Blanden, A. R. Recombinant Manganese Peroxidase Reduces A2E Burden in Age-Related and Stargardt’s Macular Degeneration Models. Rejuvenation Res 2018, 21 (6), 560–571. https://doi.org/10.1089/rej.2018.2146.
• DeRosa, J. R.; Moyer, B. S.; Lumen, E.; Wolfe, A. J.; Sleeper, M. B.; Bianchi, A. H.; Crawford, A.; McGuigan, C.; Wortel, D.; Fisher, C.; Moody, K. J.; Blanden, A. R. RPtag as an Orally Bioavailable, Hyperstable Epitope Tag and Generalizable Protein Binding Scaffold. Biochemistry 2018, 57 (21), 3036–3049. https://doi.org/10.1021/acs.biochem.8b00170.
• Tinklepaugh, J.; Smith, B. M.; Nie, Y.; Moody, K.; Grohn, K.; Bou-Abdallah, F.; Doyle, R. P. Saposin B Binds the Lipofuscin Bisretinoid A2E and Prevents Its Enzymatic and Photooxidation. ChemPhotoChem 2017, 1 (6), 256–259. https://doi.org/10.1002/cptc.201700039.